ALS ONE

United In ALS research and care.

ALS ONE is an unprecedented partnership of ALS researchers, clinicians, and care providers who have joined forces to advance critical research towards a cure while simultaneously providing essential equipment and resources to individuals currently living with the disease.

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No one is ever on the ALS journey alone.

Research

A partnership of world-leading ALS researchers focused on a cure

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Care

Providing care and essential resources for those who need it most

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Fundraising

Critical funding is necessary to further our united research and care

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Working together

With the strength of the most caring community, we advance research towards treatments leading to an ultimate cure for ALS while providing equipment and resources to individuals living with the disease now in order to ensure the very best support, access to treatment, and quality of life for them during their journey with the currently 100% terminal disease.

FACES OF ALS – Honor your ALS Hero!

Although for us and all impacted, every month is ALS Awareness Month, we are honored to commemorate the official month (May), by featuring our Faces of ALS gallery on social media for the 10th year in a row. Tributes are submission-based and it’s our honor to include anyone and everyone who would like to be included.

Click HERE to submit your tribute.

Recordings now available!

Recordings from all segments of our 7th annual ALS Research Symposium, which was held November 13-15, 2024, are now available via links on the Symposium website under each title. Whether you were able to join us but would like to rewatch, or if you missed it and are seeing the presentations for the first time, we know you’ll be inspired by hearing from over 50 speakers in total, all working towards a cure for ALS. A profound showing of brilliance, unity, collaboration, respect and kindness.

Click HERE to view.

ALS Research Publication Review Series

Review 5: “What do you think caused your ALS?” (Aired on 12/17/24)

Our 2nd review of two under the umbrella of AI in ALS Research, aired on December 17, 2024, spotlighting the publication entitled, “What do you think caused your ALS? An analysis of the CDC national amyotrophic lateral sclerosis patient registry qualitative risk factor data using artificial intelligence and qualitative methodology” with featured publication authors, Dr. Danielle Boyce, DPA, MPH, Principal Investigator, Real World Evidence at ALS TDI and Jamie Raymond, MPH, Epidemiologist at the CDC, along with panelists: Dr. John Novak, MD, Dr. Nadia Sethi, Brian Andre, and Jen DiMartino. This webinar features a poignant conversation about the analysis of an important survey that was completed by over 3,000 participants in the CDC and Prevention’s National ALS Registry who answered the question, “What do you think caused your ALS?”.

Click HERE to view the webinar.

Click HERE to read the publication.

Introducing the ALS ACE Initiative

Announcing a powerful new initiative to advance ALS research, of which we are a proud support partner! Together with the Sean M. Healey & AMG Center for ALS at Massachusetts General Hospital and the Les Turner ALS Center at Northwestern Medicine, we are thrilled to announce the launch of the Acceleration Centers of Enrollment (ACE) initiative: The ACE initiative aims to accelerate enrollment and operational improvements in ALS clinical research by increasing access to clinical trials, expanded access protocols, and non-therapeutic research studies. Support for the ACE initiative comes from an Anonymous donor, ALS ONE, and the Les Turner ALS Foundation.

The initiative will be led by a team of clinical investigators from both Mass General and Northwestern. The Mass General team will be comprised of Merit Cudkowicz, M.D., MS.C., Sabrina Paganoni, M.D., Ph.D., and Doreen Ho, M.D. Senda Ajroud-Driss, M.D., will lead the team at Northwestern. Between the two centers, the ACE initiative will provide funding for staff, training, and infrastructure to accelerate participation in research, ultimately broadening access to potential treatments and programs for people living with ALS.

“We need transformative initiatives to change the trajectory of ALS research and care,” said Dr. Paganoni. “With programs like ACE coming to fruition, we are forging new paths for those who desire to contribute to research and gain access to clinical trials, expanded access and other important studies.”

The HEALEY ALS Platform Trial has been a leader in pioneering innovation and advancing research in ALS. There is tremendous interest in participating in this study as well as other exciting research projects. The ACE initiative will improve access and efficiency, funding training and salaries of additional staff, and ultimately broadening access for people with ALS to potential treatments and programs.

“ALS ONE is honored to be a support partner of the Acceleration Centers of Enrollment (ACE) initiative. This innovative program will significantly enhance access to critical clinical trials and research studies for people living with ALS” said Jennifer DiMartino, Executive Director of ALS ONE. “ACE is a vital step towards faster, more efficient research and ultimately, finding treatments and a cure for ALS.”

Read the full press release about The ACE initiative HERE.

Events

May 31, 2025

MAY 1-31, 2025 - Faces of ALS - Gallery of courage & strength.

SUBMIT YOUR TRIBUTE TO HONOR YOUR ALS HERO FOR ALS AWARENESS MONTH. Each day on our social channels, as we do each May, we will be featuring some of the incredibly inspiring individuals who are currently living with ALS or who have lost their battle to the disease. If you would like to submit a tribute for a loved one – or you are living with ALS and would like to be featured – it would be our utmost honor. Simply complete the form via the link below and upload 1-4 photos and we’ll post during May. These tributes are submission-based and it's our honor to include anyone and everyone who would like to be included. At ALS ONE, every month is ALS Awareness Month and we’re not done until we’re ALS DONE.

SUBMIT YOUR TRIBUTE

June 2, 2025

LG4 DAY at Fenway Park

Join us at Fenway Park in celebration of Lou Gehrig Day - a night to bring awareness to the fight against ALS! We have limited seats available and if interested, please email Ashley Corbin at ashley@alsone.org. Game time is 7:10pm when the Sox take on the Angels.

June 4, 2025

June 2-4 ALS RIDE FOR HOPE 2.0

If you're interested in joining a group of amazing and highly committed cyclists who will cycle approximately 150 miles from Oxford, ME to Boxford, MA in June of 2025 to raise funds to advance critical ALS research and provide equipment and resources to individuals who are currently living with the disease, registration is now open and all are welcome!

INFO & REG HERE