United In ALS research and care.

ALS ONE is an unprecedented partnership of ALS researchers, clinicians, and care providers who have joined forces to advance critical research towards a cure while simultaneously providing essential equipment and resources to individuals currently living with the disease.

Working together and funding research for a cure tomorrow while providing equipment and resources to individuals living with ALS today.

Research

Research

A partnership of world-leading ALS researchers focused on a cure

Get Involved

Care

Providing care and essential resources for those who need it most

Fundraising

Fundraising

Critical funding is necessary to further our united research and care

Working together

With the strength of the most caring community, we advance research towards treatments leading to an ultimate cure for ALS while providing equipment and resources to individuals living with the disease now in order to ensure the very best support, access to treatment, and quality of life for them during their journey with the currently 100% terminal disease.

ALS Research Publication Review Series

REVIEW 3: “Longitudinal Biomarkers in Amyotrophic Lateral Sclerosis.”

Our 1st review of two under the umbrella of ALS Biomarkers, aired on August 27, 2024, spotlighting the publication entitled, “Longitudinal Biomarkers in Amyotrophic Lateral Sclerosis.” We were honored to be joined by two of the authors, Dr. James Berry, MD, MPH, Director of the MGH ALS clinic and Chief of the Division of ALS & MND at MGH, and Dr. Robert Bowser, PhD, Chief Scientific Officer at Barrow Neurological Institute. Joining our Executive Director, Jennifer DiMartino on the panel for this review, is Dr. Stephen Johnson, Neurologist at Mayo Clinic & NEALS NICE Committee Member. Jean Swidler, Founder & Exec. Dir of End the Legacy, and NEALS Research Ambassador; and Lori Larson Heller, NEALS Research Ambassador & PAC Member. We hope you enjoy the webinar and we thank all who so generously participated to help the ALS community.

👓 We also invite you to read the publication by going to: https://onlinelibrary.wiley.com/doi/full/10.1002/acn3.51078


Introducing the ALS ACE Initiative

Announcing a powerful new initiative to advance ALS research, of which we are a proud support partner! Together with the Sean M. Healey & AMG Center for ALS at Massachusetts General Hospital and the Les Turner ALS Center at Northwestern Medicine, we are thrilled to announce the launch of the Acceleration Centers of Enrollment (ACE) initiative: The ACE initiative aims to accelerate enrollment and operational improvements in ALS clinical research by increasing access to clinical trials, expanded access protocols, and non-therapeutic research studies. Support for the ACE initiative comes from an Anonymous donor, ALS ONE, and the Les Turner ALS Foundation.

The initiative will be led by a team of clinical investigators from both Mass General and Northwestern. The Mass General team will be comprised of Merit Cudkowicz, M.D., MS.C., Sabrina Paganoni, M.D., Ph.D., and Doreen Ho, M.D. Senda Ajroud-Driss, M.D., will lead the team at Northwestern. Between the two centers, the ACE initiative will provide funding for staff, training, and infrastructure to accelerate participation in research, ultimately broadening access to potential treatments and programs for people living with ALS.

“We need transformative initiatives to change the trajectory of ALS research and care,” said Dr. Paganoni. “With programs like ACE coming to fruition, we are forging new paths for those who desire to contribute to research and gain access to clinical trials, expanded access and other important studies.”

The HEALEY ALS Platform Trial has been a leader in pioneering innovation and advancing research in ALS. There is tremendous interest in participating in this study as well as other exciting research projects. The ACE initiative will improve access and efficiency, funding training and salaries of additional staff, and ultimately broadening access for people with ALS to potential treatments and programs.

“ALS ONE is honored to be a support partner of the Acceleration Centers of Enrollment (ACE) initiative. This innovative program will significantly enhance access to critical clinical trials and research studies for people living with ALS” said Jennifer DiMartino, Executive Director of ALS ONE. “ACE is a vital step towards faster, more efficient research and ultimately, finding treatments and a cure for ALS.”

Read the full press release about The ACE initiative HERE.

Events

November 13, 2024
11/13-15, 2024: ALS RESEARCH SYMPOSIUM
NOV 13, 14 & 15th! Our 6th Annual ALS Research Symposium is quickly approaching and it promises to be our best yet! Come gather with us from afar (held via Zoom so that anyone can attend easily from anywhere in the world), for our highly anticipated 3-day annual conference and listen in on presentations and talks from many of the world’s most prominent leaders in ALS research. Registration is free but required and the link will be open soon.
10th Annual SNOW BALL GALA
March 1, 2025
10th Annual SNOW BALL GALA
SAVE THE DATE for our 10th Annual SNOW BALL GALA! 2025's most exciting, important, and heartwarming night of the year will be held at the Westin Seaport in Boston, MA! Tickets and Sponsorship info will be announced soon! In the meantime, be sure to save the date because this will be ONE night that you won't want to miss. 💚💙